L9L (p.Leu9Leu) variant of CYP2C19 (Cytochrome P450 2C19)
L9L (p.Leu9Leu) in CYP2C19 (Cytochrome P450 2C19) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
L9L (p.Leu9Leu) variant details
- p.Leu9Leu
- gnomAD 10-94762732-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.407
- CADD 2.19
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available
- CYP2C19 VAMP-seq nonsynonymous scores: score 0.919
- Literature evidence available