L67L (p.Leu67Leu) variant of CYP2C19 (Cytochrome P450 2C19)
L67L (p.Leu67Leu) in CYP2C19 (Cytochrome P450 2C19) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
L67L (p.Leu67Leu) variant details
- p.Leu67Leu
- gnomAD 10-94775090-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.486
- CADD 13.30
- PolyPhen-2 0.00
- SIFT 0.61
- Population evidence available
- Structural context available
- CYP2C19 VAMP-seq nonsynonymous scores: score 0.494
- Literature evidence available