K48K (p.Lys48Lys) variant of CYP2C19 (Cytochrome P450 2C19)
K48K (p.Lys48Lys) in CYP2C19 (Cytochrome P450 2C19) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
K48K (p.Lys48Lys) variant details
- p.Lys48Lys
- gnomAD 10-94762849-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.0867
- CADD 0.91
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available
- CYP2C19 VAMP-seq nonsynonymous scores: score 1.05
- Literature evidence available