K28V (p.Lys28Val) variant of CYP2C19 (Cytochrome P450 2C19)
K28V (p.Lys28Val) in CYP2C19 (Cytochrome P450 2C19) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
K28V (p.Lys28Val) variant details
- p.Lys28Val
- gnomAD 10-94762786-A-AGT
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.486
- CADD 18.90
- Population evidence available
- Structural context available
- CYP2C19 VAMP-seq nonsynonymous scores: score 0.99
- Literature evidence available