I47V (p.Ile47Val) variant of CYP2C19 (Cytochrome P450 2C19)
I47V (p.Ile47Val) in CYP2C19 (Cytochrome P450 2C19) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
I47V (p.Ile47Val) variant details
- p.Ile47Val
- gnomAD 10-94762844-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.0705
- REVEL 0.02
- MetaLR 0.08
- MetaSVM -1.02
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 1.00
- Population evidence available
- Structural context available
- CYP2C19 VAMP-seq nonsynonymous scores: score 0.877
- Literature evidence available