G62G (p.Gly62Gly) variant of CYP2C19 (Cytochrome P450 2C19)
G62G (p.Gly62Gly) in CYP2C19 (Cytochrome P450 2C19) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
G62G (p.Gly62Gly) variant details
- p.Gly62Gly
- rs1848387943
- gnomAD 10-94775075-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.483
- CADD 13.80
- PolyPhen-2 0.02
- SIFT 0.13
- Most common in the East Asian population (allele frequency 2.8e-05)
- Structural context available
- CYP2C19 VAMP-seq nonsynonymous scores: score 0.086
- Literature evidence available