G32A (p.Gly32Ala) variant of CYP2C19 (Cytochrome P450 2C19)
G32A (p.Gly32Ala) in CYP2C19 (Cytochrome P450 2C19) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
G32A (p.Gly32Ala) variant details
- p.Gly32Ala
- gnomAD 10-94762798-TG-T
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.513
- CADD 23.20
- Most common in the South Asian population (allele frequency 0.00044)
- Structural context available
- CYP2C19 VAMP-seq nonsynonymous scores: score 0.247
- Literature evidence available