F65L (p.Phe65Leu) variant of CYP2C19 (Cytochrome P450 2C19)
F65L (p.Phe65Leu) in CYP2C19 (Cytochrome P450 2C19) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The record also includes experimental measurements and structural context.
F65L (p.Phe65Leu) variant details
- p.Phe65Leu
- rs202036394
- NCI-TCGA Cosmic COSV6490
- cosmic curated COSV64907
- 1000Genomes rs202036394
- Variant assessed as somatic; moderate impact.
- Missense
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available
- CYP2C19 VAMP-seq nonsynonymous scores: score 0.986