F4F (p.Phe4Phe) variant of CYP2C19 (Cytochrome P450 2C19)
F4F (p.Phe4Phe) in CYP2C19 (Cytochrome P450 2C19) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
F4F (p.Phe4Phe) variant details
- p.Phe4Phe
- rs1009356509
- gnomAD 10-94762717-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.331
- CADD 0.98
- Most common in the Finnish in Finland (FIN) population (allele frequency 3.8e-05)
- Structural context available
- CYP2C19 VAMP-seq nonsynonymous scores: score 1.01
- Literature evidence available