D49D (p.Asp49Asp) variant of CYP2C19 (Cytochrome P450 2C19)
D49D (p.Asp49Asp) in CYP2C19 (Cytochrome P450 2C19) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
D49D (p.Asp49Asp) variant details
- p.Asp49Asp
- rs777673347
- gnomAD 10-94762852-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.0815
- CADD 0.87
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available
- CYP2C19 VAMP-seq nonsynonymous scores: score 0.823
- Literature evidence available