D46D (p.Asp46Asp) variant of CYP2C19 (Cytochrome P450 2C19)
D46D (p.Asp46Asp) in CYP2C19 (Cytochrome P450 2C19) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
D46D (p.Asp46Asp) variant details
- p.Asp46Asp
- rs1482062620
- gnomAD 10-94762843-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.0919
- CADD 1.97
- Most common in the Non-Finnish European population (allele frequency 5.8e-05)
- Structural context available
- CYP2C19 VAMP-seq nonsynonymous scores: score 0.538
- Literature evidence available