C10* (p.Cys10Ter) variant of CYP2C19 (Cytochrome P450 2C19)
C10* (p.Cys10Ter) in CYP2C19 (Cytochrome P450 2C19) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data, experimental measurements, and structural context.
C10* (p.Cys10Ter) variant details
- p.Cys10Ter
- ExAC rs779922341
- gnomAD rs779922341
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.607
- CADD 35.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available
- CYP2C19 VAMP-seq nonsynonymous scores: score 0.537