Y62C (p.Tyr62Cys) variant of CYP2B6 (Cytochrome P450 2B6)
Y62C (p.Tyr62Cys) in CYP2B6 (Cytochrome P450 2B6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
Y62C (p.Tyr62Cys) variant details
- p.Tyr62Cys
- gnomAD rs1310178879
- Missense
- Variant Prioritization Score for Impact Estimate 0.547
- REVEL 0.52
- MetaLR 0.67
- MetaSVM -0.04
- CADD 25.30
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available