V65D (p.Val65Asp) variant of CYP2B6 (Cytochrome P450 2B6)
V65D (p.Val65Asp) in CYP2B6 (Cytochrome P450 2B6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.72 / 1. The record also includes population frequency data and structural context.
V65D (p.Val65Asp) variant details
- p.Val65Asp
- ExAC rs771866784
- gnomAD rs771866784
- Missense
- Variant Prioritization Score for Impact Estimate 0.716
- REVEL 0.81
- MetaLR 0.65
- MetaSVM 0.51
- CADD 25.70
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available