V5L (p.Val5Leu) variant of CYP2B6 (Cytochrome P450 2B6)
V5L (p.Val5Leu) in CYP2B6 (Cytochrome P450 2B6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
V5L (p.Val5Leu) variant details
- p.Val5Leu
- ESP rs147304516
- ExAC rs147304516
- TOPMed rs147304516
- gnomAD rs147304516
- Missense
- Variant Prioritization Score for Impact Estimate 0.0747
- REVEL 0.02
- MetaLR 0.12
- MetaSVM -1.00
- CADD 0.57
- SIFT 0.60
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available