V5I (p.Val5Ile) variant of CYP2B6 (Cytochrome P450 2B6)
V5I (p.Val5Ile) in CYP2B6 (Cytochrome P450 2B6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
V5I (p.Val5Ile) variant details
- p.Val5Ile
- cosmic curated COSV60700
- ESP rs147304516
- ExAC rs147304516
- TOPMed rs147304516
- Missense
- Variant Prioritization Score for Impact Estimate 0.07
- REVEL 0.01
- MetaLR 0.11
- MetaSVM -0.97
- CADD 0.72
- PolyPhen-2 0.04
- SIFT 0.53
- Most common in the HGDP:UYGUR population (allele frequency 0.083)
- Structural context available