V5D (p.Val5Asp) variant of CYP2B6 (Cytochrome P450 2B6)
V5D (p.Val5Asp) in CYP2B6 (Cytochrome P450 2B6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
V5D (p.Val5Asp) variant details
- p.Val5Asp
- gnomAD rs1287423251
- Missense
- Variant Prioritization Score for Impact Estimate 0.302
- REVEL 0.35
- MetaLR 0.20
- MetaSVM -0.91
- CADD 9.19
- PolyPhen-2 0.37
- SIFT 0.08
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available