T67M (p.Thr67Met) variant of CYP2B6 (Cytochrome P450 2B6)
T67M (p.Thr67Met) in CYP2B6 (Cytochrome P450 2B6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
T67M (p.Thr67Met) variant details
- p.Thr67Met
- cosmic curated COSV10013
- 1000Genomes rs138264188
- ESP rs138264188
- ExAC rs138264188
- Missense
- Variant Prioritization Score for Impact Estimate 0.443
- REVEL 0.47
- MetaLR 0.55
- MetaSVM -0.28
- CADD 22.90
- PolyPhen-2 1.00
- SIFT 0.04
- Most common in the 1KG:GBR population (allele frequency 0.011)
- Structural context available