T67K (p.Thr67Lys) variant of CYP2B6 (Cytochrome P450 2B6)
T67K (p.Thr67Lys) in CYP2B6 (Cytochrome P450 2B6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
T67K (p.Thr67Lys) variant details
- p.Thr67Lys
- 1000Genomes rs138264188
- ESP rs138264188
- ExAC rs138264188
- TOPMed rs138264188
- Missense
- Variant Prioritization Score for Impact Estimate 0.486
- REVEL 0.57
- MetaLR 0.50
- MetaSVM -0.35
- CADD 23.00
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available