T26S (p.Thr26Ser) variant of CYP2B6 (Cytochrome P450 2B6)
T26S (p.Thr26Ser) in CYP2B6 (Cytochrome P450 2B6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.
T26S (p.Thr26Ser) variant details
- p.Thr26Ser
- rs33973337
- UniProt VAR 025206
- 1000Genomes rs33973337
- ESP rs33973337
- Missense
- Variant Prioritization Score for Impact Estimate 0.0832
- REVEL 0.02
- MetaLR 0.10
- MetaSVM -0.98
- CADD 0.01
- PolyPhen-2 0.00
- SIFT 0.79
- Most common in the HGDP:BIAKA population (allele frequency 0.14)
- Structural context available
- Literature evidence available