T26I (p.Thr26Ile) variant of CYP2B6 (Cytochrome P450 2B6)
T26I (p.Thr26Ile) in CYP2B6 (Cytochrome P450 2B6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
T26I (p.Thr26Ile) variant details
- p.Thr26Ile
- Ensembl rs2144653863
- Missense
- Variant Prioritization Score for Impact Estimate 0.126
- REVEL 0.05
- MetaLR 0.16
- MetaSVM -0.94
- CADD 3.67
- PolyPhen-2 0.04
- SIFT 0.18
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available