S4R (p.Ser4Arg) variant of CYP2B6 (Cytochrome P450 2B6)
S4R (p.Ser4Arg) in CYP2B6 (Cytochrome P450 2B6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
S4R (p.Ser4Arg) variant details
- p.Ser4Arg
- gnomAD 19-40991317-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.166
- REVEL 0.21
- MetaLR 0.13
- MetaSVM -0.91
- CADD 0.08
- PolyPhen-2 0.26
- SIFT 0.31
- Population evidence available
- Structural context available
- Literature evidence available