S4G (p.Ser4Gly) variant of CYP2B6 (Cytochrome P450 2B6)
S4G (p.Ser4Gly) in CYP2B6 (Cytochrome P450 2B6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
S4G (p.Ser4Gly) variant details
- p.Ser4Gly
- gnomAD 19-40991315-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.168
- REVEL 0.09
- MetaLR 0.12
- MetaSVM -1.06
- CADD 8.04
- PolyPhen-2 0.00
- SIFT 0.35
- Population evidence available
- Structural context available
- Literature evidence available