R59Q (p.Arg59Gln) variant of CYP2B6 (Cytochrome P450 2B6)
R59Q (p.Arg59Gln) in CYP2B6 (Cytochrome P450 2B6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
R59Q (p.Arg59Gln) variant details
- p.Arg59Gln
- cosmic curated COSV57843
- ExAC rs755839000
- gnomAD rs755839000
- Missense
- Variant Prioritization Score for Impact Estimate 0.0992
- REVEL 0.07
- MetaLR 0.11
- MetaSVM -1.01
- CADD 0.76
- PolyPhen-2 0.07
- SIFT 0.42
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available