R59* (p.Arg59Ter) variant of CYP2B6 (Cytochrome P450 2B6)
R59* (p.Arg59Ter) in CYP2B6 (Cytochrome P450 2B6) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data and structural context.
R59* (p.Arg59Ter) variant details
- p.Arg59Ter
- cosmic curated COSV57842
- ESP rs371545330
- ExAC rs371545330
- gnomAD rs371545330
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.69
- CADD 35.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available