R29L (p.Arg29Leu) variant of CYP2B6 (Cytochrome P450 2B6)
R29L (p.Arg29Leu) in CYP2B6 (Cytochrome P450 2B6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data, published literature, and structural context.
R29L (p.Arg29Leu) variant details
- p.Arg29Leu
- gnomAD 19-40991391-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.0678
- REVEL 0.03
- MetaLR 0.00
- MetaSVM -0.98
- CADD 0.17
- PolyPhen-2 0.04
- SIFT 0.18
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available