P36T (p.Pro36Thr) variant of CYP2B6 (Cytochrome P450 2B6)
P36T (p.Pro36Thr) in CYP2B6 (Cytochrome P450 2B6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
P36T (p.Pro36Thr) variant details
- p.Pro36Thr
- gnomAD 19-40991411-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.321
- REVEL 0.15
- MetaLR 0.01
- MetaSVM -1.14
- CADD 9.95
- PolyPhen-2 0.06
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available