P31S (p.Pro31Ser) variant of CYP2B6 (Cytochrome P450 2B6)
P31S (p.Pro31Ser) in CYP2B6 (Cytochrome P450 2B6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
P31S (p.Pro31Ser) variant details
- p.Pro31Ser
- cosmic curated COSV10465
- gnomAD rs1464764331
- Missense
- Variant Prioritization Score for Impact Estimate 0.502
- REVEL 0.39
- MetaLR 0.59
- MetaSVM 0.06
- CADD 15.10
- PolyPhen-2 0.30
- SIFT 0.05
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available