N25D (p.Asn25Asp) variant of CYP2B6 (Cytochrome P450 2B6)
N25D (p.Asn25Asp) in CYP2B6 (Cytochrome P450 2B6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
N25D (p.Asn25Asp) variant details
- p.Asn25Asp
- gnomAD 19-40991378-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.194
- REVEL 0.03
- MetaLR 0.13
- MetaSVM -0.97
- CADD 10.80
- PolyPhen-2 0.04
- SIFT 0.30
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available