L51P (p.Leu51Pro) variant of CYP2B6 (Cytochrome P450 2B6)
L51P (p.Leu51Pro) in CYP2B6 (Cytochrome P450 2B6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
L51P (p.Leu51Pro) variant details
- p.Leu51Pro
- TOPMed rs1240426164
- gnomAD rs1240426164
- Missense
- Variant Prioritization Score for Impact Estimate 0.312
- REVEL 0.21
- MetaLR 0.01
- MetaSVM -0.83
- CADD 22.90
- PolyPhen-2 1.00
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available