L39I (p.Leu39Ile) variant of CYP2B6 (Cytochrome P450 2B6)
L39I (p.Leu39Ile) in CYP2B6 (Cytochrome P450 2B6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, published literature, and structural context.
L39I (p.Leu39Ile) variant details
- p.Leu39Ile
- gnomAD 19-40991420-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.148
- REVEL 0.18
- MetaLR 0.08
- MetaSVM -0.93
- CADD 0.02
- PolyPhen-2 0.01
- SIFT 0.61
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available
- Literature evidence available