L19V (p.Leu19Val) variant of CYP2B6 (Cytochrome P450 2B6)
L19V (p.Leu19Val) in CYP2B6 (Cytochrome P450 2B6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
L19V (p.Leu19Val) variant details
- p.Leu19Val
- ExAC rs770247931
- TOPMed rs770247931
- gnomAD rs770247931
- Missense
- Variant Prioritization Score for Impact Estimate 0.138
- REVEL 0.08
- MetaLR 0.15
- MetaSVM -1.01
- CADD 0.00
- PolyPhen-2 0.03
- SIFT 0.60
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available