L15I (p.Leu15Ile) variant of CYP2B6 (Cytochrome P450 2B6)
L15I (p.Leu15Ile) in CYP2B6 (Cytochrome P450 2B6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
L15I (p.Leu15Ile) variant details
- p.Leu15Ile
- ExAC rs755125783
- gnomAD rs755125783
- Missense
- Variant Prioritization Score for Impact Estimate 0.14
- REVEL 0.04
- MetaLR 0.18
- MetaSVM -0.89
- CADD 0.99
- PolyPhen-2 0.14
- SIFT 0.72
- Most common in the Non-Finnish European population (allele frequency 4.5e-06)
- Structural context available