L11F (p.Leu11Phe) variant of CYP2B6 (Cytochrome P450 2B6)
L11F (p.Leu11Phe) in CYP2B6 (Cytochrome P450 2B6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
L11F (p.Leu11Phe) variant details
- p.Leu11Phe
- ExAC rs750518496
- gnomAD rs750518496
- Missense
- Variant Prioritization Score for Impact Estimate 0.0897
- REVEL 0.06
- MetaLR 0.15
- MetaSVM -1.02
- CADD 0.15
- PolyPhen-2 0.00
- SIFT 0.34
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available