G63E (p.Gly63Glu) variant of CYP2B6 (Cytochrome P450 2B6)
G63E (p.Gly63Glu) in CYP2B6 (Cytochrome P450 2B6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data and structural context.
G63E (p.Gly63Glu) variant details
- p.Gly63Glu
- gnomAD rs1969135108
- Missense
- Variant Prioritization Score for Impact Estimate 0.658
- REVEL 0.57
- MetaLR 0.76
- MetaSVM 0.74
- CADD 25.00
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available