G41E (p.Gly41Glu) variant of CYP2B6 (Cytochrome P450 2B6)
G41E (p.Gly41Glu) in CYP2B6 (Cytochrome P450 2B6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
G41E (p.Gly41Glu) variant details
- p.Gly41Glu
- ExAC rs778199309
- gnomAD rs778199309
- Missense
- Variant Prioritization Score for Impact Estimate 0.501
- REVEL 0.42
- MetaLR 0.06
- MetaSVM -1.01
- CADD 23.20
- PolyPhen-2 1.00
- SIFT 0.36
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available