G33R (p.Gly33Arg) variant of CYP2B6 (Cytochrome P450 2B6)
G33R (p.Gly33Arg) in CYP2B6 (Cytochrome P450 2B6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
G33R (p.Gly33Arg) variant details
- p.Gly33Arg
- gnomAD rs1378385483
- Missense
- Variant Prioritization Score for Impact Estimate 0.457
- REVEL 0.34
- MetaLR 0.04
- MetaSVM -1.15
- CADD 23.20
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available