F55I (p.Phe55Ile) variant of CYP2B6 (Cytochrome P450 2B6)
F55I (p.Phe55Ile) in CYP2B6 (Cytochrome P450 2B6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
F55I (p.Phe55Ile) variant details
- p.Phe55Ile
- gnomAD 19-40991468-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.395
- REVEL 0.25
- MetaLR 0.21
- MetaSVM -0.88
- CADD 11.00
- PolyPhen-2 0.30
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available