D64E (p.Asp64Glu) variant of CYP2B6 (Cytochrome P450 2B6)
D64E (p.Asp64Glu) in CYP2B6 (Cytochrome P450 2B6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
D64E (p.Asp64Glu) variant details
- p.Asp64Glu
- 1000Genomes rs534437956
- ExAC rs534437956
- TOPMed rs534437956
- gnomAD rs534437956
- Missense
- Variant Prioritization Score for Impact Estimate 0.157
- REVEL 0.10
- MetaLR 0.32
- MetaSVM -0.58
- CADD 10.10
- PolyPhen-2 0.90
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available