A10S (p.Ala10Ser) variant of CYP2B6 (Cytochrome P450 2B6)
A10S (p.Ala10Ser) in CYP2B6 (Cytochrome P450 2B6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
A10S (p.Ala10Ser) variant details
- p.Ala10Ser
- cosmic curated COSV60700
- Missense
- Variant Prioritization Score for Impact Estimate 0.204
- REVEL 0.06
- MetaLR 0.18
- MetaSVM -0.95
- CADD 5.74
- PolyPhen-2 0.08
- SIFT 0.68
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available