Y65H (p.Tyr65His) variant of CYP2A6 (Cytochrome P450 2A6)
Y65H (p.Tyr65His) in CYP2A6 (Cytochrome P450 2A6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
Y65H (p.Tyr65His) variant details
- p.Tyr65His
- TOPMed rs1967190483
- gnomAD rs1967190483
- Missense
- Variant Prioritization Score for Impact Estimate 0.477
- REVEL 0.40
- CADD 23.30
- PolyPhen-2 0.46
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available