V92M (p.Val92Met) variant of CYP2A6 (Cytochrome P450 2A6)
V92M (p.Val92Met) in CYP2A6 (Cytochrome P450 2A6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
V92M (p.Val92Met) variant details
- p.Val92Met
- ExAC rs777098140
- TOPMed rs777098140
- gnomAD rs777098140
- Missense
- Variant Prioritization Score for Impact Estimate 0.271
- REVEL 0.25
- CADD 13.60
- PolyPhen-2 0.24
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 4.9e-05)
- Structural context available