V92L (p.Val92Leu) variant of CYP2A6 (Cytochrome P450 2A6)
V92L (p.Val92Leu) in CYP2A6 (Cytochrome P450 2A6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
V92L (p.Val92Leu) variant details
- p.Val92Leu
- ExAC rs777098140
- TOPMed rs777098140
- gnomAD rs777098140
- Missense
- Variant Prioritization Score for Impact Estimate 0.196
- REVEL 0.17
- CADD 6.49
- PolyPhen-2 0.01
- SIFT 0.09
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available