V23L (p.Val23Leu) variant of CYP2A6 (Cytochrome P450 2A6)
V23L (p.Val23Leu) in CYP2A6 (Cytochrome P450 2A6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
V23L (p.Val23Leu) variant details
- p.Val23Leu
- TOPMed rs1967199537
- Missense
- Variant Prioritization Score for Impact Estimate 0.164
- REVEL 0.04
- CADD 7.26
- PolyPhen-2 0.03
- SIFT 0.51
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available