V23A (p.Val23Ala) variant of CYP2A6 (Cytochrome P450 2A6)
V23A (p.Val23Ala) in CYP2A6 (Cytochrome P450 2A6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
V23A (p.Val23Ala) variant details
- p.Val23Ala
- TOPMed rs1967199498
- Missense
- Variant Prioritization Score for Impact Estimate 0.172
- REVEL 0.10
- CADD 6.73
- PolyPhen-2 0.00
- SIFT 0.68
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available