V110I (p.Val110Ile) variant of CYP2A6 (Cytochrome P450 2A6)
V110I (p.Val110Ile) in CYP2A6 (Cytochrome P450 2A6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
V110I (p.Val110Ile) variant details
- p.Val110Ile
- 1000Genomes rs72549435
- ESP rs72549435
- ExAC rs72549435
- TOPMed rs72549435
- Missense
- Variant Prioritization Score for Impact Estimate 0.207
- REVEL 0.05
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 0.81
- Most common in the African/African-American population (allele frequency 7.3e-05)
- Structural context available