S99G (p.Ser99Gly) variant of CYP2A6 (Cytochrome P450 2A6)
S99G (p.Ser99Gly) in CYP2A6 (Cytochrome P450 2A6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
S99G (p.Ser99Gly) variant details
- p.Ser99Gly
- ExAC rs749005083
- TOPMed rs749005083
- gnomAD rs749005083
- Missense
- Variant Prioritization Score for Impact Estimate 0.214
- REVEL 0.15
- CADD 18.30
- PolyPhen-2 0.01
- SIFT 0.05
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available