R88K (p.Arg88Lys) variant of CYP2A6 (Cytochrome P450 2A6)
R88K (p.Arg88Lys) in CYP2A6 (Cytochrome P450 2A6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
R88K (p.Arg88Lys) variant details
- p.Arg88Lys
- ESP rs372082998
- ExAC rs372082998
- TOPMed rs372082998
- gnomAD rs372082998
- Missense
- Variant Prioritization Score for Impact Estimate 0.137
- REVEL 0.14
- CADD 0.42
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the East Asian population (allele frequency 0.0002)
- Structural context available