R77Q (p.Arg77Gln) variant of CYP2A6 (Cytochrome P450 2A6)
R77Q (p.Arg77Gln) in CYP2A6 (Cytochrome P450 2A6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
R77Q (p.Arg77Gln) variant details
- p.Arg77Gln
- 1000Genomes rs201250423
- ExAC rs201250423
- TOPMed rs201250423
- gnomAD rs201250423
- Missense
- Variant Prioritization Score for Impact Estimate 0.14
- REVEL 0.05
- CADD 15.90
- PolyPhen-2 0.03
- SIFT 0.07
- Most common in the Finnish in Finland (FIN) population (allele frequency 9.5e-05)
- Structural context available