R76P (p.Arg76Pro) variant of CYP2A6 (Cytochrome P450 2A6)
R76P (p.Arg76Pro) in CYP2A6 (Cytochrome P450 2A6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
R76P (p.Arg76Pro) variant details
- p.Arg76Pro
- ExAC rs752300065
- gnomAD rs752300065
- Missense
- Variant Prioritization Score for Impact Estimate 0.515
- REVEL 0.37
- CADD 22.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available